Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium
Purpose
The investigators are performing this research study to understand the role of sleep disturbance on the incidence/severity of delirium after surgery. The investigators will study the brain using a polysomnography device (PSG), which records the brain's electrical activity during sleep.
Condition
- Delirium
Eligibility
- Eligible Ages
- Between 60 Years and 100 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Over 60 years of age - Inpatient and scheduled for surgical procedure at MGH
Exclusion Criteria
- Blindness, deafness or the inability to speak English - Inability to provide informed consent Objective Drop Criteria - Post-operative intubation greater than 24 hours
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| MGH Surgery Patients | PSG data will be collected, and delirium assessments conducted, on patients undergoing surgery at MGH. |
|
More Details
- Status
- Completed
- Sponsor
- Massachusetts General Hospital
Study Contact
Detailed Description
During this study, PSG recordings will be collected and a sleep questionnaire will be administered to participants on the night before surgery in order to establish level of preexisting sleep disturbance. Delirium assessments will be conducted during the postoperative period. On postoperative days 0 and 1, blood will be collected for analysis. Further cognitive, quality of life and pain questionnaires will be administered perioperatively.