Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Pain
Purpose
The aim of this proposal is to investigate brain response and connectivity changes evoked by video-guided acupuncture imagery treatment (VGAIT) and verum and sham acupuncture in healthy and patient populations to elucidate the underlying brain mechanisms of mind-body interaction, imagery, and acupuncture.
Condition
- Pain
Eligibility
- Eligible Ages
- Between 18 Years and 60 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Right handed healthy male and female adults aged 18-60 - No contraindications to fMRI scanning
Exclusion Criteria
- Current or past history of major medical, neurological, or psychiatric illness - Any pain disorder - Pregnancy - Non-fluent speaker of English
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Basic Science
- Masking
- None (Open Label)
Arm Groups
Arm | Description | Assigned Intervention |
---|---|---|
Experimental Healthy Volunteers |
In this experiment, we will apply a crossover design in healthy subjects. Each subject will receive four treatments in four separate sessions: 1) VGAIT, 2) VGAIT control condition, 3) real acupuncture, and 4) sham acupuncture. Each session will be separated by at least 7 days. Subjects will participate in five experimental sessions: a training and familiarity behavioral session and four fMRI sessions during which the subject will receive one of the four treatments. |
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Recruiting Locations
Massachusetts General Hospital
Charlestown, Massachusetts 02129
Charlestown, Massachusetts 02129
More Details
- Status
- Unknown status
- Sponsor
- Massachusetts General Hospital