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Purpose

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Condition

Eligibility

Eligible Ages
Over 40 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • 40 years of age or older - English fluency and literacy - Seeking care for basal joint pain - Tender over basal joint - Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction) - Radiographic evidence of Eaton stage 1 and 2 only

Exclusion Criteria

  • Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment - Inability or unwillingness to participate in a trial study - Rheumatoid Arthritis or other inflammatory disorder diagnoses - Post-traumatic osteoarthritis - Patients on Coumadin/Steroids/NSAIDs/Tylenol - Diabetes Mellitus - Pregnant or lactating women - Basal joint arthritis of Eaton stage 3 - Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Turmeric 		Subjects in this group will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.
  • Dietary Supplement: Turmeric
    Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.
Placebo Comparator
Control 		Subjects in this group will receive a placebo pill 3 times per day for 6 weeks.
  • Other: Placebo
    Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Recruiting Locations

Massachusetts General Hospital
Boston, Massachusetts 02114
Contact:
Neal Chen, MD
617-726-4700
nchen1@mgh.harvard.edu

More Details

Status
Recruiting
Sponsor
Massachusetts General Hospital

Study Contact

Neal Chen, M.D.
617-726-4700
nchen1@mgh.harvard.edu

Notice

Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.