Quality of Pediatric Resuscitation in a Multicenter Collaborative

Purpose

This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.

Conditions

  • Cardiac Arrest
  • Cardiopulmonary Arrest

Eligibility

Eligible Ages
Between 0 Years and 17 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patient received chest compressions for at least 1 minute - Patient between gestational age ≥37 weeks and 17 years of age - Patient had a quality of CPR measurements device (eg., Zoll Medical chest compression sensor) in place during chest compressions

Exclusion Criteria

  • Patient on extracorporeal membrane oxygenation (ECMO) therapy at beginning of CPR event

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Pediatric Cardiac Arrests Pediatric cardiac arrests requiring chest compressions for at least 1 minute managed at clinical centers identified as part of standard clinical operations.

Recruiting Locations

Massachusetts General Hospital
Boston, Massachusetts 02114
Contact:
Michael Flaherty

More Details

Status
Recruiting
Sponsor
Children's Hospital of Philadelphia

Study Contact

Vinay Nadkarni, MD, MS
215-590-7430
nadkarni@chop.edu

Detailed Description

Cardiac arrests in children are a major public health problem. Thousands of children each year in the USA are treated with cardiopulmonary resuscitation (CPR) and managed after their cardiac arrest. Neurological outcomes following these in-hospital CPR events are often abnormal. As children with neurological deficits following CPR are a major burden for families and society, improving neurological outcomes through superior chest compression delivery during CPR and optimal care and management after cardiac arrest is an important clinical goal. Therefore, the objective of this investigation is to obtain evidentiary support to associate the relationship of quantitative CPR quality data (depth, rate, chest compressions (CC) fraction, compression release) during CPR, post-cardiac arrest care (PCAC) and patient survival in those children who suffer an arrest within the study (RES-Q) Network.